Sinclair DNA Study

  • 523 members
Are you a member of the Sinclair DNA Study project?
Craig St Clair Craig St Clair
October 7 @ 9:01pm
Steve, the results on my cousin's (Craig St. Clair) Big Y were complete as of 9/30/19. Can you help us interpret this? When Craig Sinclair was co-administrator he told me this could help us match to others who've done the Big Y and have verified paper trails. What do you recommend we do at this point? Thank you in advance! Kathryn
Steve St Clair
October 30 @ 4:30pm
Hi Kathryn, I've posted a quick video so you can get to the same place I did and look around a bit. There's more to do which I'll explain soon.
Craig St Clair
November 9 @ 7:59pm
Thanks so much for your video explanation! It was very helpful!
Kathryn K2a10
November 16 @ 12:44pm
This is so fascinating! Thank you for the explanation. Very generous of you.
Tim Sinclair Sinclair Tim Sinclair Sinclair has a question!
October 24 @ 12:18pm
As an absolute baffled beginner where DNA comes in, please can someone explain what a big Y DNA test is, as compared with the Y DNA test which I had done (67 marker) with familytree dna. Records have confirmed that my fourth great grandfather Donald Sinclair was born in 1730, Perthshire, Scotland. Beyond that, it was surmised from other cousin's DNA possible links that his father was a John Sinclare born in Caithness, 1700. I'm at the proverbial brick wall, really, at the Donald Sinclair point. And of the familytree dna sub-test options, what do they mean and which to chose. I have almost 1,500 matches suggested from that original test. So, where to begin? Tim Sinclair (
Steve St Clair
October 30 @ 4:03pm
Different way of saying what Peter said above... STR testing, even out to 67 markers can be a bit unreliable because the alleles tested can mutate even in 1 generation - even those alleles considered stable. SNPs are believed to mutate only once and then never again. That's what Big Y tests and compares, and it tests for tens of thousands of parts of the human chromosome, not just 67 parts. As Bennett Greenspan (Chairman of FTDNA) told me just before it came out, this test "will connect the branches to the leaves." Those alive today are the leaves. The big branches are our early haplotypes (like R1b). The little branches that connect to the leaves are the final part of the puzzle. For instance, I now know families I connect with back in the 1400s. Our Caithness lineage now knows it shares a male ancestor with the Cumming (Comyn) family back in the mid 1100s. That's the importance of doing Big Y testing.
Tim Sinclair Sinclair
November 2 @ 1:45pm
Thank you Peter and Steve, especially the video link - just seemed what I wanted. But it wouldn't load. Tried with wifi hotspot and mobile data. It would have shown me how to find the Big Y page, which I've been unable to do. Nothing on on the familytreedna home or its other links has a hint of such. So frustrating.
Tim Sinclair Sinclair
November 3 @ 5:02am
FOUND IT - the order form that is! I've ordered the Big Y, although not being an "expert" I'm sure I'll be back here asking questions - and hope for guidance. Thanks
Stephen St. Clair
November 3 @ 9:03am
Also feel free to call me at 917-676-6788 any time you have questions.
Gail Hardy      791594/T124143 Gail Hardy 791594/T124143
October 8 @ 6:44am
I stumbled across my Saint-Clair ancestors again. My 27th great grandmother, Agnes de Saint-Clair, born 1054 in St Clair Sur Elle, Manche, Basse-Normandie, France, and died before 1100 in Bramber, Sussex, England. Her parents are Waldron de Saint-Clair, Count de Saint-Clair, born about 1005 in St Clair Sur Elle, Mance, Basse-Normandie, France, and died 1057 in Barnstable, Devon, England; and Helena "le Bon", born about 1030 in France and died in France.
lynn huddleston gregory
October 24 @ 3:55pm
What would cause that number to be so high? I don't have a clue about how to read these things.
Gail Hardy 791594/T124143
October 25 @ 3:19am
My guess would be that there are a whole bunch of very small SNPs.
lynn huddleston gregory
October 25 @ 5:36pm
I did another download on gedmatch from Ancestry and the number for it is DC3401226. Would this help with the SNP's?
Gail Hardy 791594/T124143
October 26 @ 8:40am
I ran our kits together and we've still got that 1,322 SNPs on Chromosome 6.
lynn huddleston  gregory lynn huddleston gregory
October 24 @ 4:03pm
Just a question, looking at the mtDNA results for this group how are they listed? The first time I looked my results were on like page 3 ir 4 now its on page 1. What causes them to move?
Gail Hardy 791594/T124143
October 25 @ 3:24am
They move because more people keep testing and are being added to the roster. We also have an excellent Administrator who is on his toes and tries to keep the list current with very few un-categorized members.
lynn huddleston gregory
October 25 @ 4:49pm
Ok, thanks. I truly never realized how complicated all this could get
Steve St Clair Steve St Clair
August 17 @ 4:09pm
Danny, I can't post new pics in existing threads, so the answer to your question is here. I see your big Y 700 results when I click in the section I marked with a red #1 which is on the homepage of your FTDNA kit. Click on either of the two on the right and You'll see all 700 of your markers. If you click on the word "Matches" on the left in my #1 image, you'll see the Big Y STR results applied to what used to be just the 37, 67, or 111-marker level. They also have migrated in Big Y SNP results into it, but still not the Yfull markers. If you look at our results chart in my section 2 of the image, you'll see I'm keeping up with that manually. Yfull is not owned or associated with FTDNA, but they do cooperate with Yfull analysis. Of 417 markers checked, you and I are only off on 3 STRs. Don't know why they checked that number. Probably because I'm not yet tested on Y700, something I'm remedying this weekend.
Steve St Clair
August 17 @ 4:17pm
Daniel, did you order your new BAM file for your Y700 yet? I can show you how to do that and re-submit it to Yfull. I'll be doing that when mine comes in. We all should.
Daniel Redmond
August 18 @ 8:23am
Steve, thank you for the information and taking time to post the photos. It's a big help to not only me, but I'm sure others. I have already uploaded my BAM for the Y700 to YFull. I believe I had done that about a month ago. So my results are at both YFull and the Big Tree. Now I'm just wondering what more I can do to help with the Sinclair DNA study. I'm still reviewing my Redman/Redmond line and am hopeful that someday I can pinpoint the generation that changed from Sinclair/St. Clair/Sinkler to Redman/Redmond but I know it is an uphill battle.
Gregory St. Clair Gregory St. Clair
July 21 @ 12:27pm
Steve, do I need to re-up the YFull with the new Y700 or does that happen automatically?
Steve St Clair
August 11 @ 2:53pm
On their site, I don't see the Y700 listed as one that Yfull accepts. I've got an email off to them now.
Steve St Clair
August 16 @ 4:00pm
Greg and others, please click the audio link just next to this thread re: Y500 and Y700.
Daniel Redmond
August 16 @ 5:36pm
Steve, I had uploaded my Big Y700 to Y-Full but am unclear if they have taken all of the entries or just limited it to the Big Y500.
Steve St Clair
August 17 @ 4:12pm
Daniel, see answer with accompanying image just next to this thread.
Steve St Clair Steve St Clair
August 16 @ 3:59pm
This is a recording of a call I made to one of the experts at Family Tree DNA on the Y500 and Y700 testing and how they interact with Big Y. She also explains the need to get a new BAM file once your results come in and then send it off to Yfull -
Peter Sinclair Peter Sinclair
August 5 @ 1:10pm
Hi Steve, for some reason I am still missing on the results page despite making sure I am opted in to sharing. I joined in 2006 and all was ok for years then my name disappeared. In the old days you referred to me as Peter (Perthshire) Sinclair if that reminds you. My earliest ancestor was in Perthshire in 1725. My kit is #62937. My FTDNA testing puts me in R Z251 and YSEQ identified the sub clade Z16944+. STR and SNP results show my particular line to be a pretty lonely one but I guess that we are still talking about genetic changes that took place about 3,000 years ago. Autosomal comparisons are broad as you know, but those that include the Sinclair surname tend to have Caithness, Orkney or Shetland origins as you might expect. One remote but very interesting match suggests that I share a few segments of DNA with the Sinclairs of Rattar back in the 17th Century, including John, Master of Caithness and his direct descendants. I am therefore making progress towards my objective, which was to see if I could confirm the expected link with Caithness. It is disappointing not to find family links with anyone, but perhaps this autosomal link with the Sinclairs of Rattar might yield something. Has your research touched on this branch of our history and are you aware of project members that might be relevant? Regards, Peter.
Steve St Clair
August 11 @ 2:49pm
Peter, can you email me at ? We'll get to the bottom of this in the next few days.
Jerry Wright Jerry Wright
August 5 @ 11:28pm
Steve: I just check on my uncle Stan Wright's listing #B166902 and my own #590783 and I wonder if our Y500 tests have been updated into the spreadsheet. Also my uncle Stan #B166902 has recently did the upgrade to the Y700 and I just ordered my Y700 update for Kit No. 590783. Can you tell when this data might be put into the spreadsheet Thank You
Steve St Clair
August 11 @ 2:48pm
I'll check your results this week Jerry and do the update above the "Lineage" you're in.
Kathryn K2a10 Kathryn K2a10
April 19 @ 11:35am
Hello All. This is Kathryn from New Orleans. My great-grandfather FW Sinclair moved here from Gloucester, Virginia area to marry my sweet great-grandmother back in 1907. This line of Sinclairs has been in the Mobjack Bay/York River/Rappahannock River region of VA since the 1730s. I'd like to learn which DNA group my line of Sinclairs belongs to. Being a lady, I can only learn my mtDNA so I'll rely on the family men to share this information. I appreciate your time and attention to my request. Thank you!
Steve St Clair
April 28 @ 6:11pm
I suspect you'll be related to Alexander Sinkler given the Rappahannock River region you mentioned. Do you have men in the family who carry the surname and can do the DNA testing?
Steve St Clair
June 2 @ 4:02pm
My advice is to trace forward in FW's line moving toward the present. Try to find living male descendants to test that way.