The attached is how I calculated the Time to Most Recent Common Ancestor (TMRCA) for branch R-FGC15254, which is in the A2 grouping.
William Sinclair who departed this life Sept 13, 1826 In the 49 year of his age. Anyone have any information on William Sinclair buried in the Old Methodist? Cemetery?
Place Taken: St Clairsville, Belmont County, Ohio
Date Taken: 13 Oct 2002
Owner: Skip Magyar
I want to share with you my analysis of the BigY tests for the Alexander Sinkler (Group 12) grouping. Disclaimer is that I have not validated lineages with the exception of the Redman lines. For reference, I am kit B100027.
LINEAGE AND SNP ZS4578
If lineages are correct, I believe SNP ZS4578 is tied to either Alexander Sinkler or his son, Wayman. The way to confirm is if someone takes a BigY700 test and has a solid paper trail to Alexander via a son OTHER than Wayman, the results should either show positive for having ZS4578 or negative. Positive should mean Alexander (or his father/grandfather/etc.) was born with the mutation and passed it down to both sons (Wayman and the other test taker’s ancestor). If the result is negative, then Wayman was born with the mutation and passed it down to all of his sons. Similarly, if my chart is incorrect and one or more of the BigY test takers did not descend from Alexander’s son, Wayman, but a different son, we would expect Alexander then also carried the ZS4578 mutation.
What is exciting is that two members (B179231 & IN77152) do not descend from Alexander but their lines do trace back to Scotland. B179231 has taken a SNP Package test and is confirmed positive for ZS4576 but negative for ZS4578. Add the fact that I am also negative for ZS4578 and do not believe I descend from Alexander (via a non-parental event), provides strong evidence that ZS4578 is tied to Alexander or Wayman. IN77152 has indicated he plans to upgrade to BigY sometime in the future. His results should provide us with a better estimate to our common ancestor.
SHORT TANDEM REPEAT (STR)
When looking at the STR values from Y-37/67/111 tests, we have to remember that not only the difference in value is important but also the mutation rate. Fast mutation rates for STRs means a more recent common ancestor than a slower mutating STR. When looking at IN77152’s STR values, you will see that DYS393 and DYS495 have different values then the mode. Both of these alleles have slow mutation rates, which supports a more distant common ancestor.
LIST OF EQUIVALENT SNPS TO ZS4576
A Single Nucleotide Polymorphisms (SNP, pronounced “snip”) is a mutation on a point of the Y Chromosome from the ancestral value. Off to the left of the chart, you will see a list of SNPs. These are “equivalent” to ZS4576, meaning there isn’t enough information to determine which SNP occurred first, second, third, etc. All that is currently known is that the BigY test takers are positive for all of these. If a member takes a BigY700 test and the results show negative for any of the list of SNPs, this would “break up” the list and should form a new branch on the Haplogtree.
Why is this important? SNP mutations are more stable than STRs. It has been determined that the average SNP mutation occur between 83-144 years. Unlike STRs, SNPs very rarely mutate back to their ancestral value so they are better at determining time to most recent ancestor. If a new branch is formed, we can narrow down the timeline to our shared common ancestor. Additionally, determining a Sinclair/St. Clair/Sinkler ancestor that created a SNP, say ZS4576 or one of the equivalent SNPs, would be a major breakthrough in our research.
Ancestry update of our origins
Daniel Redmond, you're doing great work here!
Steve I traced both GG Schulmister and Rilling to this town
I am dumbfounded. Don't understand this comment
Group 12 – Alexander Sinkler Connection
I used David Vance’s SAPP (Still Another Phylogeny Program) tool to map out the Short Tandem Repeat (STR) values for those kits in Group 12. The thicker the line, the more confident the connection. You may need to download the photo to be able to zoom in. There are 25 kits in this group with ten being Y37, eight Y67, and seven at Y111. To be able to dive deeper would require those with Y37 or Y67 to consider upgrading to Y111 or BigY.
I would like to eventually map this out using SNPs since they are much more reliable than STRs, which are subject to convergence. However, this would require more cousins to upgrade to BigY. Additionally, having access to the lineage path for each descendant back to Alexander would help because we could figure out which son, grandson, or great-grandson (etc.) of Alexander the mutated SNP occurred.
Of the 25 kits, it appears 10 have either done the BigY or an individual SNP package test. I’m the sole “Redman” in this group. I’m awaiting the results of a Y37 test I purchased for a 3rd cousin twice removed. Once the results confirm the Y-DNA connection, I plan on upgrading his kit to BigY700 (with his permission). This should result in a new branch under R-ZS4576.
The below is from another project administrator (Lucas McCaw) in which he describes different situations for upgrading to BigY700. I’ve written the situation we are currently in with Group 12 but really, this is the case for any of the groups.
“Haven’t upgraded to BigY yet but other Y DNA surname matches have.”
In this case, as soon you start having members of your family upgrade to BigY, you enter the realm of solving genealogical issues in your paternal line. In the original days of BigY, it was often thought to only be relevant to ancient archaeological information. We now know that BigY data is EXTREMELY USEFUL in solving mysteries about your own recent genealogy, and putting to rest certain theories that have been proposed but until now there was no actual way of confirming. BigY helps that immensely.
In this situation, the BEST strategy to use BigY with genealogy is to have at least one BigY test for each (documented) Most Distant Common Ancestor for each line. That will show how each branch falls in relation to each other in the same surname family. However, that is only the first step and still leaves open questions. To maximize your ability to solve mysteries, it requires a second male for each branch to test. That male should be the MOST DISTANT known cousin descended from that Most Distant Common Ancestor. By testing both males in this line, you are able to confirm the exact mutations that the ancestor was born with, and then able to position him with other branches and much more clarity. And IF that documented male has not done Y DNA testing at all, you should use the sale prices available to have a kit order form them. Once you get all lines in the same family using this strategy, the entire structure of a family going back to its origins can be established. Gaps can then be filled by targeted testing of specific males in the family.
The Summer Sale has begun.
A NEW BiGY-700 is $399 USD (a savings of $50 USD)
If you log in to a Kit and place an order for a Test in the Shopping Cart, you will get the Summer Sale Price.
Father's Day Sale is here! Lots of value in upgrading to BigY 700. SNP testing is a more accurate way to determine MRCA than STRs.
FTDNA DNA Day sale price listing. Ends 26 April.
Jon. Sinkler, younger. Bottom-right on this list of menin the parochin of Biggar, 1640.