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T2 mtDNA

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Research

October 2017. I have submitted the revision of a paper on T2e from project pants to a peer reviewed international genetics journal. It's pretty hard core and fussy, so will see the eventual outcome. I was required to cut original submission by about half, so alot of the interesting bits had to get eliminated which they felt read too much like a genealogy project. Note to those in T2e1, please send FASTA files if you have not already since want to make sure get all of those submitted by the publication date of the article.  FB

In 2014, a commentary based on the T2e work of 2013 and earlier (see below) was accepted in the European Journal of Human Genetics. http://www.nature.com/ejhg/journal/vaop/ncurrent/full/ejhg2014232a.html

In 2013, our study was published that investigated two important branches of T2e. The work led to several new branches being recognized with their own notations in Phylotree build 16 and 17.  If the link does not work, please let me know.

http://dx.doi.org/ doi: 10.4172/2329-9002.1000121  


On 16 September 2010 a manuscript based on 450 full mitochondrial sequences for T haplogroup was submitted to a journal for possible publication. This paper on the T_FGS study was accepted for publication in December 2010 by the Journal of Genetic Genealogy, complete text can be found here: http://www.jogg.info/62/files/Pike.pdf 

This paper has created a more detailed phylogenetic chart based on the full genetic scan results. The complete list of defining SNPs can be found here: http://www.jogg.info/62/files/QuickRef.pdf
The authors have been able to identify and name many previously unnamed subgroups of mtDNA Haplogroup T. They have also been able to use genetic diversity within several of these subgroups to estimate their ages. Regarding possible geographical origins for these subgroups, despite the relatively large number of samples that were worked with, they think that it will take far more samples before reliable conclusions can be drawn.


Have you done the Full Mitochondrial Sequence (FMS)? Are you still “just” T, T2, T2b – or other undefined groups? In order to find new subclades, please also consider donating your sequence to research. Read more.


A paper from the T_FGS study was accepted for publication in December 2010 by the Journal of Genetic Genealogy, complete text can be found here: http://www.jogg.info/62/files/Pike.pdf 
This paper has created a more detailed phylogenetic chart based on the full genetic scan results. The complete list of defining SNPs can be found here: http://www.jogg.info/62/files/QuickRef.pdf

For testers with HVR1 only (mtDNA-test) or HVR1+2 (mtDNAplus) we have also sorted these into the known subclades, but in most cases the Full Sequence test (FGS) is necessary to verify cubclade assignment, as the defining SNPs are often in the Codeing Region.

(Earlier results:)
Please see the following website for project results.
http://www.kipp-blake-families.ca/T2Results.htm
http://www.kipp-blake-families.ca/T2aResults.htm
http://www.kipp-blake-families.ca/T2bResults.htm
http://www.kipp-blake-families.ca/T2cResults.htm
http://www.kipp-blake-families.ca/T2eResults.htm