- To advance our understanding of the split between the indigenous Americans from their Eurasian progenitors through thoughtful analysis of genetic information found on the Y Chromosome.
- To gather as many Y-DNA samples from native Mexican and Southwestern USA lineages as possible. Native lineages are defined as those belonging to specific subclades of Y-DNA Haplogroups Q and C.
- In addition to the current geographic area known as Mexico to also include lands that have been historically associated with Mexico, these are primarily the southwestern border states of: Texas, New Mexico, Arizona, and California.
- To analyze available SNP's and STR-based haplotypes of project participants and group them into appropriately similar sub-groupings. By grouping the project members we hope that patterns will emerge which might provide clues about deep lineage associations such as geographic origins, tribal origins, etc.