Haplogroup L0 originated in sub-Saharan Africa approximately 110,000 years ago and is the less common of the two phylogenetic daughters who descended from our globally-shared most recent female ancestor, "Mitochondrial Eve." Since L0 first arose in southeastern Africa, it grew and spread throughout the region, migrating and evolving for more than 100,000 years. During that time, some L0 groups transformed from hunter-gatherers to agriculturalists, while others, like the Khoisan people of southern Africa, continued practicing the older way of subsistence. Today, around 25% of the southeast African groups and a smaller proportion of Eastern and Central Africans belong to haplogroup L0. In addition, some people of African matrilineal ancestry in the Americas carry one of the most common subgroups of L0, known as L0a. Haplogroup L0a is approximately 33,000 years old, making it one of the youngest daughters of the ancient haplogroup L0. The distribution of L0a in Sub-Saharan Africa is quite broad, suggesting that it spread successfully with migrations of the last 30 millennia. Furthermore, it occurs in high frequency among African-descendant communities in the Americas and was most likely carried across the Atlantic during the centuries-long transatlantic slave trade. Haplogroup L0a1 is approximately 19,000 years old, and it occurs in populations across central, eastern, and southern Africa. Its distribution and higher frequencies along the Indian Ocean coasts suggest that it arose in southeastern Africa and was possibly transported to the Americas by the Portuguese or the French who captured, enslaved, and traded people along what is today Mozambique. Haplogroup L0a2 is approximately 20,000 years old and most likely arose in central or eastern Africa. Today, L0a2 is most common among people of modern-day Kenya and Ethiopia and is less common among African-descendent communities in the Americas. L0a2b is prevalent among the Mbuti people, a hunter-gatherer group in the eastern the Democratic Republic of the Congo. Haplogroup L0d is approximately 67,000 years old, making it the oldest of the daughters of L0 and among the oldest haplogroups in the world. It most likely arose in southern Africa where it currently is still found. L0d occurs in the highest frequency among the hunter-gatherer groups from South Africa, Namibia, and Botswana, including the traditional Khoisan people. Haplogroup L0f is approximately 56,000 years old, making it the second oldest daughter of haplogroup L0. Today, L0f is most commonly found in southern Africa as well as among a few populations in Somalia in the horn of Africa and across the Red Sea in the Arabian peninsula. Haplogroup L0k is approximately 31,000 years old and is primarily found in southern Africa. Today, L0k occurs mostly among isolated groups in the southern stretches of the continent, including among the last few remaining hunter-gatherer groups who call that region their home.