The name appears to have originated in Calinog, Iloilo County, Panay Island, Philippines, but may have had other origins. There are many with this surname in the U.S.A.

Reportedly, the early Spanish had each Filipino household choose up a surname from lists of names posted on their church wall. Calinog had surnames beginning with "C," Passi with "P," and so forth. As such, it is possible that all Caspillo are closely related within the last 450 years, approximately.

If Caspillo represents a Spanish male admixture on the surname line, this will show up in the haplogroup results.