I1>Z58+ and I1>Z63+- Background

Background

Greetings!

The I1>Z58+ and I1>Z63+ project focuses on the investigation of the Z58+ and Z63+ subgroups of the I1 haplogroup. It evolved from the "I1 recLOH - YCAII a,b = 21,21" project, as the discovery of new SNP's made it possible to home in on the specifics of each of the original 21,21 groups in our study. Thus, this project is now SNP-based, and to participate you just need to have tested positive for either Z58 (Z58+) or Z63 (Z63+),  or any of their downstream SNP's - terminal SNP's highlighted below:  

*M253 > DF29

*M253 > DF29 > Z63

*M253 > DF29 > Z58

*M253 > DF29 > Z58 > Z138/Z139

*M253 > DF29 > Z58 > Z138/Z139 > L211

*M253 > DF29 > Z58 > Z59

*M253 > DF29 > Z58 > Z59 > Z382

*M253 > DF29 > Z58 > Z59 > Z60 > L573

*M253 > DF29 > Z58 > Z59 > Z60/Z62

*M253 > DF29 > Z58 > Z59 > Z60/Z62 > Z73

*M253 > DF29 > Z58 > Z59 > Z60/Z62 > L803

*M253 > DF29 > Z58 > Z59 > Z60/Z62 > L803 > L802

*M253 > DF29 > Z58 > Z59 > Z60/Z62 > Z140/Z141

*M253 > DF29 > Z58 > Z59 > Z60/Z62 > Z140/Z141 > L592

*M253 > DF29 > Z58 > Z59 > Z60/Z62 > Z140/Z141 > L338

Eligibility

You are welcome to join this Project if:

1.     You tested positive, or you are a close relative of someone in your surname project who tested positive for Z63 (Z63+). 

2.      You tested positive, or you are a close relative of someone in your surname project who tested positive for Z58, or any SNP downstream of Z58 such as Z138, Z139, Z59, Z382, Z60, Z61, Z62, L338, Z73, Z62, Z140, Z141, L211, L592, L573, L803 or L802.

Mailing List

Once you join the I1>Z58+ and I1>Z63+ Project, we will add you to our private Mailing List at Yahoo. You can choose to opt out later if you wish.

Z58+ and Z63+  'Surname SNP Tree'

A SNP tree with kit numbers, surnames, and most distant ancestors' places of origin will be provided for participants. The SNP tree will be narrow and focused directly downstream of Z58+ and Z63+. This Surname SNP Tree will be updated regularly and should help illuminate which downstream SNPs could be tested next. We also hope, over time, that the visual presentation will assist members researching historical origins as well as more recent connections.

WTY

Y-DNA genealogical investigation is supported by two main piers: STR markers (short tandem repeats, such as DYS393) and SNP's. Whenever looking at a Y-DNA match, one should first make sure they share the same terminal SNP (belong to the same subgroup). Only then should one look at STR's for tMRCA calculations with genealogical purposes, because STR similarities alone are often deceiving. As SNP mutations are rare, sharing a series of SNP's means two or more individuals also share a common ancestor. The age of the mutation that led to the SNP indicates the earliest time-frame a Most Recent Common Ancestor may have lived. In other words, the younger an SNP and the smaller the number of individuals who share it, the more useful it will be to genealogical research, as it will be closer to (or within) the genealogical period, ie, after surnames started to be used in Europe.

For this reason, this Project also intends to allow joint efforts that make possible the participation of members in programs such as 'Walk Through the Y'. WTY is a program by FT DNA's Thomas Krahn, which focuses on the discovery of new SNP's. The main goal is to further the knowledge of Y-DNA subgroups by discovering "tree nodes" that lead to separate, younger branches of the Y-tree. The closer we get to the tip of the branch, the more applicable the knowledge to one's genealogical investigation. WTY has already benefited our research through the discovery of SNPs L802 and L803. These SNPs are downstream of Z60 and shed further light on one of our subgroups. Other discoveries should follow. 

Click here for more information on WTY.

I1 recLOH - YCAII a,b = 21,21

As we constantly improve and expand the Project, we will not forget our original mission, which was to investigate the shared ancestry of families that experienced recLOH mutations at YCAII a,b.  Early members of the former ‘21,21' project who test negative for both of the SNPs, Z58 and Z63, will also participate in our ongoing study.

A recLOH (Recombinational Loss of Heterozygosity) event is "a type of mutation which occurs with DNA by recombination." From a pair of equivalent (homologous), but slightly different (heterozygous) segments, a pair of identical (homozygous) segments results.

Palindromic Panel tests have been performed by Family Tree DNA to determine the nature of the recLOH events affecting the 21,21 members of this project. In particular, advanced marker DYF399X has proven to be a very good glimpse into these events. Check out DYF399X results under the Results section.

This is an exciting time in Haplogroup I1, with the new Z-series SNPs proving to be especially effective. Traditional haplotype clustering had historically placed our ‘RecLOH’ participants into the AS Generic subgroup of the I1 Haplogroup. However, discoveries of new SNPs by the researchers of the 1000 Genome Project allowed the separation of these individuals into separate families - those who are Z58+, those who are Z63+, and those who are testing negative for both of these SNPs. Initial subgrouping by known most downstream (terminal) SNP will be much more accurate going forward than traditional haplotype clustering by STR.

Please contact the project administrators if you have any questions.

Project Stats