Blood

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Initially - all BLOODs were found to be related and belong to the haplogroup 

R1b>U106>>L47>Z160>CTS3777>FGC17298>FGC17304>BY60604>FT85154

This includes descendants of Robert Blood in Massachusetts from 1630, George Blood in Philadephia from 1830 and Thomas Blood in Australia from 1860, showing all these Bloods are descended from a single man. 

Genetically the family breaks up into Derby Bloods (with marker FT85084) and Nottingham Bloods (with marker FT124365.). This split occurred around 1400AD. 

Some other surnames from the North Mercia area are closely related. including branches of HYDE, WILLIS, CHEATHAM, COKER, ASHMORE and JACKSON.   See the R-A6093 North Mercia project, https://www.familytreedna.com/groups/r-a6093-north-mercia/

However, some descendants of Richard Blood in Massachusetts (the largest well-documented group of BLOODs)  have completely different Y-DNA.  
I2a: L460>P37>CTS595>L1286>L1287>L233>Y4252+ A7111. The L233 branch is Isles. dating from Roman times.