I-M223 Y-Haplogroup Project - News

The most up-to-date version of the I-M223 tree currently under investigation can be found here.

As of 03/22/2013, the I-M223 tree configuration is as follows:

1- M223
1.1- L1228 (I2b1-X)
1.1.1- L1227 (I2b1-X)
1.2- CTS616, CTS9183
1.2.1- L1229* (Roots Group 2a)
1.2.1.1- L1230 (Roots Group 2a Section 1/446 = 9, 531 = 11)
1.2.1.2- Z2054* (Roots)
1.2.1.2.1- L812* (Roots Group 1a/446 = 8, 438 = 8)
1.2.1.2.1.1- L319 (Roots Group 1a/446 = 8, 438 = 8)
1.2.2- Z161
1.2.2.1- L801, Z76
1.2.2.1.1- Z183*
1.2.2.1.1.1- CTS6433* (Cont2a, Cont2to1, Cont1-X)
1.2.2.1.1.1.1- Z78* (Cont1-XX)
1.2.2.1.1.1.1.1- Z171* (Cont1-XXX)
1.2.2.1.1.1.1.1.1- L1198* (Cont1, Cont1a)
1.2.2.1.1.1.1.1.1.1- Z190* (Cont1b, Cont1c)
1.2.2.1.1.1.1.1.1.1.1- Z79 (Cont1c1)
1.2.2.1.1.2- CTS1977* (Cont2b/P95-)
1.2.2.1.1.2.1- P95 (Cont2b)
1.2.2.1.1.2.2- L1201 (Cont2b)
1.2.2.1.1.2.3- CTS1858
1.2.2.1.1.3- L1317, L1290 (ContX)
1.2.2.2- L623, L147.4 (Cont2c)
1.2.3- L701, L702
1.2.3.1- P78 (Cont3a)
1.2.3.1.1- L484 (Cont3a)
1.2.3.2- L699, L703 (I2b1-XX)
1.2.3.2.1- L704 (I2b1-XX1)
1.2.3.2.1.1- L1226 (I2b1-XX1)
1.2.4- M284*
1.2.4.1- L1195
1.2.4.1.1- L1193* (Isles E)
1.2.4.1.1.2 L1194 (Isles E)
1.2.4.1.2- L126, L137, L369 (Isles Limbo, Isles Sc)

06/15/2012 - Not long ago, it was a known fact that two-thirds of all individuals in the I-M223 Haplogroup would be negative for all downstream SNP's. Thanks to our group effort, we can say that as of June, 2012 that is no longer the case. Now we can trust that there is more than 99% chance that an M223+ individual will be positive for at least one downstream SNP. As of today, the new I-M223 Tree Configuration is as follows:

1- M223
1.1- L1229* (Roots)
1.1.1- L812* (Roots Group 1a/446 = 8, 438 = 8)
1.1.1.1- L319 (Roots Group 1a/446 = 8, 438 = 8)
1.1.2- L1230 (Roots Group 2a Section 1/446 = 9, 531 = 11)
1.2- Z161
1.2.1- L801
1.2.1.1- Z76* (Cont2a, Cont2b/P95-, Cont2to1, Cont1-X)
1.2.1.1.1- Z78* (Cont1-XX)
1.2.1.1.1.1- L1198 (Cont1, Cont1a, Cont1b)
1.2.1.1.1.1.1- Z79 (Cont1c)
1.2.1.1.2- P95 (Cont2b)
1.2.1.1.3- L1201 (Cont2b)
1.2.2- L623, L147.4 (Cont2c)
1.3- L701, L702
1.3.1- P78 (Cont3a)
1.3.1.1- L484 (Cont3a)
1.3.2- L699, L703 (I2b1-XX)
1.3.2.1- L704 (I2b1-XX1)
1.3.2.1.1- L1226 (I2b1-XX1)
1.4- M284*
1.4.1- L1195
1.4.1.1- L1193* (Isles E)
1.4.1.1.2 L1194 (Isles E)
1.4.1.2- L126, L137, L369 (Isles Limbo, Isles Sc)
1.5- L1228 (I2b1-X)
1.5.1- L1227 (I2b1-X)


05/31/2012 - WTY results for kit# 22066 (Sewell, M223>Z161>L801>Z76>Z78>L1198*) have been scored by Astrid Krahn. It revealed no new SNP's.

05/08/2012 - WTY participant kit# 48274 (Griffin, Roots Group 2a) had his results scored by Astrid Krahn. Coverage was of 412,910 base pairs and two new SNP's have been found: L1229 and L1230.

05/04/2012 - WTY participant kit# E5922 (Hofstee, I2b1-X) had his results scored by Astrid Krahn. Coverage was of 415,359 base pairs and two new SNP's have been found: L1227 and L1228. Kit# 83425 (Wilson, I2b1-XX) is negative for both of these, so they are not upstream SNP's. Kit# E5922 is also negative for Z76, L1193, L1194, L1195, L1226, L1201, L1198. Positive for L1196 and L1197.

05/04/2012 - WTY participant kit# 83425 (Wilson, I2b1-XX) had his results scored today. Coverage was of 423,487 base pairs and one new SNP has been revealed: L1226. Based on coverage from previous WTY's, the following participants and their sub-haplogroups can be presumed negative for this new SNP: 31781 (Games, Cont2c), 69631 (Rasey, Cont2a), 150778 (Mendes da Silva, Roots Group 1a/446 = 8, 438 = 8), 113655 (Gibbon, IslesSc Group 1). This limits L1226 to I2b1-XX.

05/03/2012 - Another WTY participant kit# 199243 (Gunning, Isles Sc) had his results scored today by Astrid Krahn at FT DNA. Coverage was of 418,587 base pairs but unfortunately no new SNP's have been discovered. This exam did cover the sites for the L1193 and L1194 SNP's, for which this participant was negative. That means all Isles English individuals should be testing for L1193 and L1194, as these SNP's are specific to the Isles English subgroup. No news yet on L1195. The exam also covered the site for Z76, and Gunning is negative for it as well. This reinforces the theory by 1,000 Genome Project volunteers that Z76 is phyloequivalent to L801 or maybe slightly upstream from it.

04/25/2011 - M223 Tree Configuration as of 04/2012:

1- M223* (I2b1-X, I2b1-XX, Roots-X, Roots/L812-)
1.1- L812* (Roots Group 1a/446 = 8, 438 = 8)
1.1.1- L319 (Roots Group 1a/446 = 8, 438 = 8)
1.2- L801* (Cont2a, Cont2b/P95-)
1.2.1- Z78* (Cont1, Cont1a, Cont1b)
1.2.1.1- Z79 (Cont1c)
1.2.2- P95 (Cont2b)
1.3- L623, L147.4 (Cont2c)
1.4- P78 (Cont3a)
1.5- M284* (Isles E)
1.5.1-L126, L137, L369 (Isles Limbo, Isles Sc)


04/25/2012 - Another WTY participant kit# 127052 (McCall, Cont1) had his results scored today by Astrid Krahn at FT DNA. Coverage was of 411,308 base pairs and one new SNP has been discovered: L1198. The next step is for us to investigate the relationship between L1198 and Z78.

04/25/2012 - WTY participant kit# 65183 (Michaels, Cont2b/P95-) had his results scored today. Coverage was of 394,577 base pairs of and one new SNP was revealed: L1201. We already know this SNP is relevant because the Cont1 WTY participant kit# 127052 is negative for it. The next step is for this SNP to be tested on a larger scale within Cont2b.

04/20/2012 - The first WTY results from our most recent initiative have been scored by Astrid Krahn. Kit# 12526 (Farmer, Isles E/I2b1a) had coverage of 392,734 base pairs and yielded the following new SNP's: L1193, L1194, L1195, L1196, L1197. The next step is for these SNP's to be tested on a larger scale.

04/08/2012 - New I2b1/M223 Discussion Forum created at Yahoo! Groups: http://groups.yahoo.com/group/I-M223/

01/31/2012 - Successful fundraising initiative takes 8 M223 Project Members to the "Walk Through the Y" program:

199243 - Gunning (Isles Sc)
12526 -  Farmer (Isles E)
127052 - McCall (Cont 1)
65183 - Michaels (Cont 2b, P95-)
83425 - Wilson (I2b1-XX)
E5922 - Hofstee (I2b1-X)
48274 - Griffin (Roots Group 2a)
22066 - Sewell (Cont1)

12/21/2011 - M223 Tree Configuration as of 12/2011:

1- M223* (I2b1-X, I2b1-XX, Roots-X, Roots/L812-)
1.1- L812 (Roots)
1.1.1- L319 (Roots)
1.2- L801* (Cont1, Cont1a, Cont1b, Cont2a, Cont2b/P95-)
1.2.1- P95 (Cont2b)
1.3- L623, L147.4 (Cont2c)
1.4- P78 (Cont3a)
1.5- M284* (Isles E)
1.5.1-L126, L137, L369 (Isles Limbo, Isles Sc)


10/18/2011 - WTY participant Mendes da Silva (Roots Group 1, DYS 446 = 8, kit# 150778) has had his results scored by the FT DNA team. The exam covered 244955 bp's and a brand new SNP has been discovered: L812. This new finding reinforces the success of the M223 WTY campaign.

10/10/2011 - Results have been scored for WTY participant Rasey (Cont2a subgroup, kit# 69631). The exam covered 231451 bp's and three brand new SNP's have been discovered: L800, L801, and V218.2.

6/30/2011 - Results have been scored for a project member who participated independently in the WTY program. Three new SNP's have been discovered in the exam of kit# 31781: L147.4, L622 and L623. The Project will hereon work with members to understand the position of these SNP's on the phylogenetic tree.

6/23/2011 - A recent fundraising campaign has made it possible for two of our project members to participate in WTY. The first participant (kit# 69631) belongs to the "Cont2a" subgroup and was co-sponsored by the Rasey Y-chromosome DNA Surname Project. The "Roots 446 = 8" participant (kit# 150778) has origins in Mediterranean Europe, as do a good number of members of the Roots subgroup. Both participants have been accepted into the program. The next step is to collect new samples, which will then be analyzed by the FT DNA team. It is a slow process, so it should be a few months before we have any news. With these two exams, we hope to finally discover an SNP, which will officially divide the Continental and Roots subgroups and maybe allow for some segmentation within those. - Aaron Salles Torres, Project Administrator

3/2011 - Aaron Salles Torres is the new Project Administrator.

10/28/2009 - The I2b2 WTY results are in, and unfortunately he was also positive for L-181. This means that this new SNP is upstream of the I2b1/I2b2 split and will not help divide I2b1. Bummer.

9/7/2009 - Our I2b1 Roots donor's WTY results are in, and unfortunately he is also L181+ and has no other new SNPs. Because he shares this L181 with our Continental donor, it does not split the Roots and Continental branches as we had hoped it might. These results now place L181 upstream of I2b1 Roots and Continental, and per previous I2* WTY results, downstream of I2*. What we need to do now is wait for the I2b2 donor's WTY results and see where he stands. If he's also positive for L181, then it's not even unique to I2b1. If he's negative, then we'll go about selectively having other I2b1 people test for it

8/2/2009 - The WTY results for our Continental donor are in, and one new SNP, L-181, has been discovered. It is unknown at this time how this SNP fits in as we are still awaiting the WTY results for the I2* donor and the I2b1 Roots donor. Stay tuned...

7/8/2009 - I2b1 Project Discussion created at DNA Forums 7/7/2009 - No WTY Results yet. 6/1/2009 - Link to Ken Nordvedt's updated "Warped Founders Tree": Warped Founders Tree 5/22/2009 - Subgrouping work is still underway. About another 100 people in the old Cont2 group still need to be run through the haplogroup prediction tool. Please double-check my results for accuracy for your own kits.

5/2/2009 - Reorganization of subgroupings is underway. 5/1/2009 - The Walk the Y Project for I2b1 is now fully funded and underway.

4/21/2009 - I have taken over administration of the I2b1 Project as the former admin no longer was able administer it. Many thanks to Grant for having administered it so well for so long. Organization will be in a state of flux for awhile. Please bear with me as I try to get my arms around this. Jane Gilbert