Single Nucleotide Polymorphism (SNP) Testing
What is a Single Nucleotide Polymorphism?
The following definition comes from the National Institutes of Health's Genetics Home Reference web site:
What are single nucleotide polymorphisms (SNPs)?
Single nucleotide polymorphisms, frequently called SNPs (pronounced “snips”), are the most common type of genetic variation among people. Each SNP represents a difference in a single DNA building block, called a nucleotide. For example, a SNP may replace the nucleotide cytosine (C) with the nucleotide thymine (T) in a certain stretch of DNA.
SNPs occur normally throughout a person’s DNA. They occur once in every 300 nucleotides on average, which means there are roughly 10 million SNPs in the human genome . . .
Of course, the types of SNPs we are interested in, the ones that help us learn about our shared paternal ancestry, occur on the y chromosome.
If you can order Family Tree DNA's Big Y test, please do so. Big Y results will help us learn more about our cluster and our shared ancestry, including what SNPs we share with other cluster members and how we differ from each other, if we do.
The members of this cluster who have tested for the SNP DF41 (also known as S524 and CTS6581) have all been DF41+. Those who have tested for the SNP CTS2501 (also known as S836) have all been CTS2501+, as well. The position of CTS2501 relative to DF41 is not yet known, but they are two distinct SNPs and not equivalent or synonymous.
DF41 and CTS2501 are downstream of DF13, which is downstream of L21 (L21>DF13>Z39589>DF41/CTS2501).
For our group's current SNP testing/Big Y status, see the DF41 section of Alex Williamson's "The Big Tree", http://www.ytree.net/DisplayTree.php?blockID=7, and YFull's R1b Tree, where member kit numbers YF08577, YF08619, and YF08776 are grouped under the SNP BY160 (below CTS2501 and Y8426): https://www.yfull.com/tree/R1b/
See also the ISOGG (International Society of Genetic Genealogy) R Tree: http://www.isogg.org/tree/ISOGG_HapgrpR.html
We strongly recommend you order Family Tree DNA's Big Y test or, at the very least, its R1b-DF41 SNP Pack.
To order the Big Y, go to your myFTDNA pages and click on "Upgrade" in the upper right of the screen. There you will see the ad for the Big Y test. Click on the blue button to the right of it to order the Big Y.
To order the R1b-DF41 SNP pack, follow the instructions below.
1. Go to your myFTDNA pages and click on "Upgrade" in the upper right of the screen.
2. Scroll down and click on the blue "Buy Now" button under "Advanced Tests".
3. In the "Test Type" box, choose "SNP Pack" from the drop down menu.
4. Scroll down, find the R1b-DF41 SNP Pack, and click "Add".
5. Complete the fields to make the purchase.
Who can join?
If you are a Family Tree DNA customer and have y-dna STR test results with the marker values described above, or most of them, and/or a match to one or more of the members of the project at 67 or more markers, you are eligible to join the R1b-41-1123 Project.
If you can join the R1b-41-1123 Project, you should also join the R-DF41 and Subclades Project and the R L21 and Subclades Project at the following links: