Single Nucleotide Polymorphism (SNP) Testing
What is a Single Nucleotide Polymorphism?
The following definition comes from the National Institutes of Health's Genetics Home Reference web site:
What are single nucleotide polymorphisms (SNPs)?
Single nucleotide polymorphisms, frequently called SNPs (pronounced “snips”), are the most common type of genetic variation among people. Each SNP represents a difference in a single DNA building block, called a nucleotide. For example, a SNP may replace the nucleotide cytosine (C) with the nucleotide thymine (T) in a certain stretch of DNA.
SNPs occur normally throughout a person’s DNA. They occur once in every 300 nucleotides on average, which means there are roughly 10 million SNPs in the human genome . . .
Of course, the types of SNPs we are interested in, the ones that help us learn about our shared paternal ancestry, occur on the y chromosome.
If you can order Family Tree DNA's Big Y-700 test, please do so. Big Y-700 results will help us learn more about our cluster and our shared ancestry, including what SNPs we share with other cluster members and how we differ from each other, if we do.
Big Y-500 and Big Y-700 testing of the members of this group has revealed that all those tested thus far are derived (positive) for the SNP BY166 (also known as Z18021), which characterizes a subclade in the major y-dna haplogroup R1b as follows: R M207> R1 M173> R1b M343> L754> L389> P297> M269> L23> L51> P310> L151> P312> Z290> L21> DF13> Z39589> DF41> FGC5572> BY168> BY166. Other SNP's downstream of BY166 and identifying family branches of the group include FGC36974 and the parallel SNP's downstream of it, FGC36982 and PF5064, and the SNP BY38518. Scientists at Family Tree DNA recently identified the newly discovered SNP FGC36981 as downstream of FGC36982.
Recent Big Y-700 test results have revealed that the BY168/BY170/BY171 block of SNPs is upstream and separate from BY166. The newly discovered SNP FT115269 is downstream of BY168/BY170/BY171 and parallel to BY166. If you have a positive result for any of these SNPs, please join this project.
See also the ISOGG (International Society of Genetic Genealogy) R Tree: http://www.isogg.org/tree/ISOGG_HapgrpR.html
We strongly recommend you order Family Tree DNA's Big Y-700 test or, at the very least, its R1b-DF41 SNP Pack.
To order the Big Y-700, go to your myFTDNA pages and click on "Upgrade" in the upper right of the screen. There you will see the ad for the Big Y test. Click on the blue button to the right of it to order the Big Y.
To order the R1b-DF41 SNP pack, follow the instructions below.
1. Go to your myFTDNA pages and click on "Upgrade" in the upper right of the screen.
2. Scroll down and click on the blue "Buy Now" button under "Advanced Tests".
3. In the "Test Type" box, choose "SNP Pack" from the drop down menu.
4. Scroll down, find the R1b-DF41 SNP Pack, and click "Add".
5. Complete the fields to make the purchase.
Who can join?
If you are a Family Tree DNA customer and have y-dna STR test results with the marker values described above, or most of them, and/or a match to one or more of the members of the project at 67 or more markers, or you have tested positive for the SNP BY166 (Z18021) or any of its downstream SNP's, you are eligible to join the R1b-41-1123 Project.
If you can join the R1b-41-1123 Project, you should also join the R-DF41 and Subclades Project and the R L21 and Subclades Project at the following links: